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Bicalutamide is a non-steroidal androgen receptor inhibitor that binds competitively to androgen receptors, blocking the effects of androgens in target tissues. Prostate carcinoma, being androgen-sensitive, responds to treatments that reduce or inhibit androgen action. Casodex is used in combination with a luteinizing hormone-releasing hormone (LHRH) analog to treat Stage D2 metastatic carcinoma of the prostate.
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✅ Description:
Casodex 50mg Tablet contains Bicalutamide, an anti-androgen medication, used for the management of prostate cancer in adult males.
- A slow-growing cancer originates in the cells of the prostate gland
- Difficulty urinating or weak urine flow
- Blood in urine or semen
- Frequent urination, especially at night
- Bone pain, weight loss without cause
- Pain while sitting or erectile dysfunction
- Regular blood tests are necessary to check for any changes in blood composition.
- Avoid excessive exposure to sunlight or UV light while taking this medicine.
- Inform your doctor if you have liver issues, heart conditions, or diabetes.
- Not recommended for:
- Women (including pregnant or breastfeeding mothers).
- Children and adolescents under 18 years.
Safety Advices
Alcohol
UNSAFE
Avoid consumption of alcohol while taking Casodex 50.
Pregnancy
UNSAFE
Casodex 50 is not recommended for use by pregnant women. Patients and their partners should use birth control while taking CALUTIDE 50MG TABLET and for 130 days after stopping the> management. Consult your doctor before taking it.
UNSAFE
Casodex 50 is not recommended for use by breastfeeding women. Consult your doctor before taking it.
Driving
UNSAFE
Do not drive or operate any machines if you feel sleepy after taking Casodex 50.
Kidney
CAUTION
No dosage adjustment of Casodex 50 is necessary for patients with kidney impairment. Consult your doctor before taking it.
Liver
CAUTION
Casodex 50 should be used with caution in patients with liver problems. Consult your doctor before taking it.
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✔️ Uses of Casodex 50
To manage prostate cancer in adult male patients
✔️ How does Casodex 50 work?
Casodex 50 inhibits cell growth and manages the spread of cancer cells from the prostate gland to other parts of the body by selectively blocking proteins responsible for the growth and development of the prostate gland (androgen receptors), which reduces the effect of androgen (the male sex hormone) in the prostate gland.
✔️ Side Effects of Casodex 50
- Hot flashes
- Pain (general, back, pelvic, abdominal)
- Asthenia (weakness)
- Nausea, constipation, diarrhea
- Peripheral edema
- Dyspnea, infection
- Hematuria, nocturia
- Anemia
✔️ Quick Suggestions:
- Exercise regularly to lose weight as obesity is also considered as a risk factor for prostate cancer.
- Casodex 50 may cause your skin to become light-sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
- If you are diabetic, monitor your blood glucose regularly while taking Casodex 50.
- Quit smoking to reduce the risk of prostate cancer.
✔️ Direction For Use Casodex 50
Take Casodex 50 as advised by your physician. Swallow it with a glass of water, and do not chew or crush it. Your doctor will decide the correct dose and duration of Casodex 50 management for you depending on your age, body weight, and disease condition. Do not stop taking Casodex 50 unless your doctor advises you to stop.
✔️ What if I have taken an overdose of Casodex 50 Tablet
Do not take more than the prescribed dose of Casodex 50 Tablet as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.
✔️ Dosage & Administration of Casodex 50
- Recommended Dose:
- Adults: One 50 mg tablet daily, with or without food.
- Timing: Morning or evening.
- Special Populations:
- Pediatric Use: Not established for safety or efficacy.
- Hepatic Impairment: Use cautiously in patients with moderate-to-severe liver impairment as the drug is extensively metabolized in the liver.
✔️ Interaction
- CYP3A4 Inhibition:
- Casodex may increase plasma levels of drugs metabolized by CYP3A4; caution with co-administered substrates.
- Anticoagulants:
- Monitor PT/INR closely if using with coumarin anticoagulants (e.g., warfarin).
✔️ Contraindications:
- Hypersensitivity to bicalutamide or any components of the tablet.
- Contraindicated for use in women, including pregnant or breastfeeding individuals.
✔️ Pregnancy & Lactation
- Pregnancy: Contraindicated due to the potential for fetal harm.
- Lactation: Not intended for use in females; no data available on excretion in breast milk.
✔️ Precautions & Warnings
- Monitor PT/INR with coumarin anticoagulant use.
- Gynecomastia and Breast Pain: Reported in males on 150 mg doses used as monotherapy.
- Glucose Tolerance: Monitor blood glucose in patients taking Casodex with LHRH agonists.
- Prostate-Specific Antigen (PSA): Regular monitoring is recommended to evaluate treatment response or progression.
✔️ Storage:
- Store at a temperature not exceeding 30°C.
- Keep in a dry place, protected from light and moisture.
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accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
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everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
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